AN OPTICAL METHOD FOR DETECTING ANESTHETICS AND OTHER LIPID-SOLUBLE COMPOUNDS

被引：6

作者：

MERLO, S ^{[1
]}

YAGER, P ^{[1
]}

BURGESS, LW ^{[1
]}

机构：

[1] UNIV WASHINGTON,CTR PROC ANALYT CHEM,SEATTLE,WA 98195

来源：

SENSORS AND ACTUATORS A-PHYSICAL | 1990年 / 23卷 / 1-3期

关键词：

D O I：

10.1016/0924-4247(90)87106-S

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We have developed a fluorescence-based fiber optic biosensor for detection of general anesthetics. It monitors anesthetic-induced changes in fluorescence emission by labeled liposomes entrapped in a hydrogel at the end of two optical fibers. We have demonstrated that this sensor is sensitive to clinically relevant concentrations of commonly used general anesthetics. The sensor may be used for remote measurements of various lipid-soluble chemicals in gas, liquid or solid phases (e.g., blood and tissue). © 1990.

引用

页码：1150 / 1154

页数：5

共 6 条

[1]

HUG CC, 1981, ANESTHESIA, V1, P161

[2]

JANOFF AS, 1982, BIOL MEMBR, P417

[3] SYNTHESIS AND CHARACTERIZATION OF A FLUORESCENCE PROBE OF THE PHASE-TRANSITION AND DYNAMIC PROPERTIES OF MEMBRANES [J].