MONO S-TRIMETHYLSILYL KETENE DITHIOACETALS AS VERSATILE TOOLS FOR THE SYNTHESIS OF ALPHA-HYDRAZINODITHIOESTERS - A NOVEL ACCESS TO ENDOTHIOPEPTIDES

被引：8

作者：

BESLIN, P

MARION, P

机构：

[1] Laboratoire de Chimie des Composés Thioorganiques (Associé au CNRS) ISMRA, Université de Caen, 14050 Caen, 6, Boulevard Maréchal Juin

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)91580-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Mono-S-trimethylsilylketene dithioacetals have been prepared from dithioesters by the action of trimethylsilyl iodide formed in situ. They were reacted easily with dialkylazodicarboxylates to give good yields of alpha-hydrazinodithioesters. The latter were transformed into thioamides or endothiodipeptides by aminolysis either with an amine or an amino acid.

引用

页码：935 / 938

页数：4

共 29 条

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