N-VINYL DERIVATIVES OF SUBSTITUTED PYRIMIDINES AND PURINES

被引：77

作者：

PITHA, J

TSO, POP

机构：

[1] Department of Radiological Sciences, Johns Hopkins University, Baltimore, Maryland

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1968年 / 33卷 / 04期

关键词：

D O I：

10.1021/jo01268a006

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation of potentially polymerizable compounds containing heterocyclic moieties of nucleic acids is described. 1-Vinyluracil was prepared by dehydrochlorination of 1-(2-chloroethyl)uracil (3). 1-Vinyl-3-methyluracil, 1-vinyl-4-ethoxy-2-pyrimidinone (7), 6-chloro-9-vinylpurine (8), and 2,6-dichloro-9-vinylpurine (9) were prepared from the unsubstituted heterocycles by a vinyl interchange reaction with vinyl acetate, catalyzed by mercuric acetate and sulfuric acid. © 1968, American Chemical Society. All rights reserved.

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页码：1341 / &

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