HYBRIDIZATION PROPERTIES OF RIBOSOMAL RNA FROM RABBIT TISSUES

The capacity of 28-S and 18-S ribosomal RNA isolated from reticulocytes and liver to hybridize to DNA has been studied. The plateau values reached by ribosomal RNA are the same, irrespective of whether ribosomal RNA from liver or from reticulocytes, or a mixture of both RNA's, are used. Moreover, ribosomal RNA from one tissue competes to form a hybrid to DNA with ribosomal RNA from the other tissue. These results have been obtained with both 28-S and 18-S ribosomal RNA and, on this basis, it has been concluded that the major base sequences of ribosomal RNA's in reticulocytes and liver are the same. © 1969.