PROPERTIES OF ALDOSE REDUCTASE FROM THE METHANOL YEAST CANDIDA-BOIDINII

被引：5

作者：

BOLEN, PL ^{[1
]}

MCCRACKEN, DA ^{[1
]}

机构：

[1] ILLINOIS STATE UNIV,NORMAL,IL 61761

来源：

JOURNAL OF FERMENTATION AND BIOENGINEERING | 1990年 / 69卷 / 04期

关键词：

D O I：

10.1016/0922-338X(90)90214-H

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In addition to xylose isomerase and sorbitol dehydrogenase activities, Candida boldinii contains aldose reductase activity. This aldose reductase does not appear to contribute to sorbitol formation because it has negligible activity with glucose as a substrate. The high activity of this aldose reductase with non-sugar aldehydes suggests that there may be industrial potential for this or other yeast aldose reductases in the production of various diols and triols, particularly since this enzyme acts irreversibly on these aldehyde substrates. © 1990.

引用

收藏

页码：211 / 214

页数：4

相关论文

共 14 条

[1] INDUCTION OF NADPH-LINKED D-XYLOSE REDUCTASE AND NAD-LINKED XYLITOL DEHYDROGENASE-ACTIVITIES IN PACHYSOLEN-TANNOPHILUS BY D-XYLOSE, L-ARABINOSE, OR D-GALACTOSE [J].

BOLEN, PL ;

DETROY, RW .

BIOTECHNOLOGY AND BIOENGINEERING, 1985, 27 (03) :302-307

[2] AFFINITY PURIFICATIONS OF ALDOSE REDUCTASE AND XYLITOL DEHYDROGENASE FROM THE XYLOSE-FERMENTING YEAST PACHYSOLEN-TANNOPHILUS [J].

BOLEN, PL ;

ROTH, KA ;

FREER, SN .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1986, 52 (04) :660-664

[3] LE MECANISME DE LA TRANSFORMATION DE GLUCOSE EN FRUCTOSE PAR LES VESICULES SEMINALES [J].

HERS, HG .

BIOCHIMICA ET BIOPHYSICA ACTA, 1956, 22 (01) :202-203

[4] ALCOHOL AND POLYOL DEHYDROGENASES ARE BOTH DIVIDED INTO 2 PROTEIN TYPES, AND STRUCTURAL-PROPERTIES CROSS-RELATE THE DIFFERENT ENZYME-ACTIVITIES WITHIN EACH TYPE [J].

JORNVALL, H ;

PERSSON, M ;

JEFFERY, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (07) :4226-4230

[5]

REXEN F, 1984, CEREAL CROPS IND USE, P103

[6] PENTOSE METABOLISM IN CANDIDA .3. TRIPHOSPHOPYRIDINE NUCLEOTIDE-SPECIFIC POLYOL DEHYDROGENASE OF CANDIDA UTILIS [J].

SCHER, BM ;

HORECKER, BL .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1966, 116 (1-3) :117-&

[7] PACHYSOLEN-TANNOPHILUS - PROPERTIES AND PROCESS CONSIDERATIONS FOR ETHANOL-PRODUCTION FROM D-XYLOSE [J].

SLININGER, PJ ;

BOLEN, PL ;

KURTZMAN, CP .

ENZYME AND MICROBIAL TECHNOLOGY, 1987, 9 (01) :5-15

[8] PURIFICATION AND PROPERTIES OF POLYOL - NADP OXIDOREDUCTASE FROM PICHIA-QUERCUUM [J].

SUZUKI, T ;

ONISHI, H .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1975, 39 (12) :2389-2397

[9] FORMATION OF POLYOLS BY THE LENS OF THE RAT WITH SUGAR CATARACT [J].

VANHEYNINGEN, R .

NATURE, 1959, 184 (4681) :194-195

[10] PROPERTIES OF THE NAD(P)H-DEPENDENT XYLOSE REDUCTASE FROM THE XYLOSE-FERMENTING YEAST PICHIA-STIPITIS [J].

VERDUYN, C ;

VANKLEEF, R ;

FRANK, J ;

SCHREUDER, H ;

VANDIJKEN, JP ;

SCHEFFERS, WA .

BIOCHEMICAL JOURNAL, 1985, 226 (03) :669-677