ENANTIOSELECTIVE CONJUGATE ADDITION OF DIETHYLZINC TO ENONES USING CHIRAL BETA-AMINOALCOHOL AS CHIRAL CATALYST OR LIGAND

被引：69

作者：

SOAI, K

OKUDO, M

OKAMOTO, M

机构：

[1] Department of Applied Chemistry, Faculty of Science, Science University of Tokyo, Shinjuku-ku, Tokyo

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 01期

关键词：

D O I：

10.1016/S0040-4039(00)71227-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically active beta-substituted ketones of up to 94% e.e. were synthesized by the enantioselective conjugate addition of diethylzinc to enones in the presence of either a catalytic or stoichiometric amount of chiral beta-aminoalcohol.

引用

页码：95 / 96

页数：2

共 12 条

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[8] CATALYTIC ASYMMETRIC INDUCTION IN ENANTIOSELECTIVE CONJUGATE ADDITION OF DIALKYLZINCS TO ENONES
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YOKOYAMA, S
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EBIHARA, K
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (17) : 4148 - 4149
[9] CATALYTIC ENANTIOSELECTIVE CONJUGATE ADDITION OF DIALKYLZINCS TO ALPHA,BETA-UNSATURATED KETONES USING NICKEL BROMIDE-N, N-DIBUTYLNOREPHEDRINE
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[J]. CHEMISTRY LETTERS, 1988, (09) : 1571 - 1572
[10] ASYMMETRIC-SYNTHESIS OF OPTICALLY-ACTIVE BETA-SUBSTITUTED KETONES BY HIGHLY ENANTIOSELECTIVE CATALYTIC CONJUGATE ADDITION OF DIALKYLZINC REAGENTS TO ENONES USING A CATALYST SYSTEM OF NICKEL(II)-CHIRAL LIGAND-ACHIRAL LIGAND IN ACETONITRILE TOLUENE
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[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1989, (08) : 516 - 517

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