SYNTHESIS OF THE CALICHEAMICIN ARYLTETRASACCHARIDE DOMAIN BEARING A REDUCING TERMINUS - COUPLING OF FULLY SYNTHETIC AGLYCONE AND CARBOHYDRATE DOMAINS BY THE SCHMIDT REACTION

被引：49

作者：

HALCOMB, RL ^{[1
]}

BOYER, SH ^{[1
]}

DANISHEFSKY, SJ ^{[1
]}

机构：

[1] YALE UNIV,DEPT CHEM,225 PROSPECT ST,NEW HAVEN,CT 06511

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1992年 / 31卷 / 03期

关键词：

D O I：

10.1002/anie.199203381

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The successful coupling of two building blocks constructed by total synthesis is described here as a route to calicheamicin (1). The aryltetrasaccharide section of 1 is shown for the first time to function as a glycosyl donor for aglycone intermediates.

引用

页码：338 / 340

页数：3

共 53 条

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