NEGATIVE RESULT - TREATMENT OF PATIENTS WITH RHEUMATOID ARTHRITIS WITH GAMMA GLOBULIN - A DOUBLE-BLIND CONTROLLED STUDY

被引：3

作者：

HERMAN, JH

JASIN, HE

SMILEY, JD

ZIFF, M

机构：

[1] USPHS Training Grant AM-05154, Rheumatic Diseases Unit, Department of Internal Medicine, The University of Texas Southwestern Medical School, Grant

[2] Department of Internal Medicine, The University of Texas Southwestern Medical School, Clinical Investigator, Veterans Administration Hospital, Dallas, Texas

[3] Rheumatic Diseases Unit, University of Texas Southwestern Medical School at Dallas, Dallas, Texas, 75235

[4] University of Texas Southwestern Medical School, Dallas, Texas

[5] Department of Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio

[6] The Veterans Administration Hospital, Dallas, Texas

来源：

ARTHRITIS AND RHEUMATISM | 1969年 / 12卷 / 05期

关键词：

D O I：

10.1002/art.1780120508

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Because agammaglobulinemic patients show a markedly increased incidence of a rheumatoid‐like arthritis, which improves after γ globulin treatment, the clinical and serological changes resulting from repeated injections of pooled human γ globulin given to adult patients with rheumatoid arthritis have been evaluated in a controlled, double‐blind study. No significant beneficial effects on laboratory or clinical parameters were observed. However, 2 of the 10 patients treated developed precipitating antibody to a β globulin component of the γ globulin preparation given. Copyright © 1969 American College of Rheumatology

引用

页码：515 / &

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