FULL-LENGTH CDNA SEQUENCE OF DENGUE TYPE-1 VIRUS (SINGAPORE STRAIN S275/90)

被引：94

作者：

FU, JL

TAN, BH

YAP, EH

CHAN, YC

TAN, YH

机构：

[1] NATL UNIV SINGAPORE,FAC MED,DEPT MICROBIOL,LOWER KENT RIDGE,SINGAPORE 0511,SINGAPORE

[2] NATL UNIV SINGAPORE,INST MOLEC & CELL BIOL,SINGAPORE 0511,SINGAPORE

来源：

VIROLOGY | 1992年 / 188卷 / 02期

关键词：

D O I：

10.1016/0042-6822(92)90560-C

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The complete nucleotide sequence and the deduced amino acid sequence of the genome of dengue virus type 1 (Singapore strain S275/90) were determined from cDNA clones. The single-stranded, positive-sense RNA is 10,718 nucleotides in length and contains a single long open reading frame of 10,188 nucleotides encoding a polyprotein of 3396 amino acids. The genomic size and organization were found to be similar to that of other dengue virus serotypes. Both the nucleotide and deduced amino acid sequences were compared with the partial sequence of DEN1 (Nauru Island) and complete sequences of DEN2 (Jamaica), DEN3 (H87), and DEN4 (Dominica) virus genomes. © 1992.

引用

页码：953 / 958

页数：6

共 15 条

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