EFFICIENT CLAISEN-TYPE CONDENSATION BETWEEN ACYL UNITS BOUND TO A MOLECULAR TEMPLATE

被引：16

作者：

SUN, SG ^{[1
]}

HARRISON, P ^{[1
]}

机构：

[1] MCMASTER UNIV,DEPT CHEM,1280 MAIN ST W,HAMILTON L8S 4M1,ONTARIO,CANADA

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 50期

关键词：

D O I：

10.1016/0040-4039(93)88025-E

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Acylation of 3,4,7,8-tetramethylglycoluril1 (1) provides the monoacyl derivative 3 which can be acylated further with LDA and acyl chlorides. The resulting symmetric or asymmetric diacyl derivatives 4 undergo efficient base-catalyzed acyl transfer to provide 2-(acylacyl)glycolurils 5,6. Thus, 1 acts as a template to allow facile condensations between acyl units.

引用

页码：7715 / 7718

页数：4

共 20 条

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