DECREASED LYMPHOID CELL MULTIPLICATION IN POST-THYMECTOMY STATE

被引：52

作者：

MEUWISSE.HJ

VANALTEN, PA

GOOD, RA

机构：

[1] the Pediatric Research Laboratories of the Variety Club Heart Hospital and Department of Microbiology, University of Minnesota, Minnesota, MN

[2] Department of Pediatrics, Minnesota, MN

[3] University of Illinois, Chicago, IL

[4] Pediatrics and Microbiology, Minnesota, MN

来源：

TRANSPLANTATION | 1969年 / 7卷 / 01期

关键词：

D O I：

10.1097/00007890-196901000-00001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The response of lymphocytes from neonatally thymectomized rats to various mitogens was studied in vitro. Lymph node lymphocytes were stimulated with phytohcmagglutinin, poleweed mitogen, or allogeneic cells treated with mitomycin C. A significant depression in the uptake of tritiated thymidine occured in response to all mitogens, although the cll survival in unstimulated cultures from thymectomized animals was normal. In vitro lymphocyte response to mitogens correlates well with tests of cell-mediated immunity in rats and, like these, appears to depend upon a thymic influence. © 1969 by The Williams & Wilkins Co.

引用

页码：1 / &

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