EFFECT OF HYDROXYAPATITE IMPREGNATION ON SKELETAL BONDING OF POROUS COATED IMPLANTS

被引:252
作者
DUCHEYNE, P
HENCH, LL
KAGAN, A
MARTENS, M
BURSENS, A
MULIER, JC
机构
[1] UNIV FLORIDA,DEPT MAT SCI & ENGN,GAINESVILLE,FL 32601
[2] UNIV FLORIDA,DEPT ORTHOPAED,GAINESVILLE,FL 32601
[3] KATHOLIEKE UNIV PELLENBERG,DEPT ORTHOPAED,BIOMAT & BIOMECH GRP,B-3041 PELLENBERG,BELGIUM
来源
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH | 1980年 / 14卷 / 03期
关键词
BIOLOGICAL MATERIALS - Bone - MICROSCOPIC EXAMINATION - Applications - MINERALOGY - Phosphates - POROUS MATERIALS - Applications - PROSTHETICS - Bonding;
D O I
10.1002/jbm.820140305
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
This paper reports on the resulting skeletal fixation of a combined porous and bioactive material. Metal plugs with a porous metal fiber coating impregnated with hydroxyapatite were implanted for 2, 4, and 12 weeks and were compared to the parent porous, nonbioactive, metal fiber material. Statistical analysis of the interfacial failure shear stress, as obtained by mechanical testing, shows there is a marked influence of hydroxyapatite impregnation on the rate of bone ingrowth and the strength of the interfacial bond the few weeks following surgery. Microscopical examination reveals that the apparent stimulation of bone ingrowth into the surface pores of the implant is the reason for the increased rate of bond formation. The results are of particular clinical interest: with an increased rate of bone ingrowth, weight bearing might be allowed much earlier, thus reducing the recuperation period.
引用
收藏
页码:225 / 237
页数:13
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