ISOMERIZATIONS OF N-(ALPHA-AMINOALKYL)-1,2,4-TRIAZOLES AND N-(ALPHA-AMINOALKYL)TETRAZOLES

被引：25

作者：

KATRITZKY, AR

JOZWIAK, A

LUE, P

YANNAKOPOULOU, K

PALENIK, GJ

ZHANG, ZY

机构：

[1] Department of Chemistry, University of Florida, Gainesville

来源：

TETRAHEDRON | 1990年 / 46卷 / 02期

关键词：

D O I：

10.1016/S0040-4020(01)85444-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title compounds exist as equilibrium mixtures of the N-1 and N-2 isomers in solution. However, the crystal structure of 3-(1-hydroxycyclohexyl)-1-(α-pyrrolidinomethyl)-1,2,4-triazole discloses only this isomer in the solid state. Evidence for the nature of the isomerization processes in solution is provided. The kinetic and thermodynamic parameters are measured and qualitatively assessed. © 1990.

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页码：633 / 640

页数：8

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