STUDIES ON AN OSTERTAGIA-OSTERTAGI STRAIN SUSPECTED TO BE RESISTANT TO BENZIMIDAZOLES

被引：7

作者：

BORGSTEEDE, FHM ^{[1
]}

GEERTS, S ^{[1
]}

DEDEKEN, R ^{[1
]}

KUMAR, V ^{[1
]}

BRANDT, J ^{[1
]}

机构：

[1] INST TROP MED,B-2000 ANTWERP,BELGIUM

来源：

VETERINARY PARASITOLOGY | 1992年 / 41卷 / 1-2期

关键词：

D O I：

10.1016/0304-4017(92)90011-W

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Four calves were infected with a susceptible (laboratory) strain of Ostertagia ostertagi and four with a field strain suspected to be resistant to benzimidazoles. After 25 days two calves from each group were treated with 3.5 mg kg-1 fenbendazole. Egg output fell to zero in all treated calves. Treated calves did not harbour worms at slaughter 35 days after infection. Significant differences between the strains were shown for ED50 values for thiabendazole in the egg hatch assay, but not in the tubulin binding assay. It is concluded that benzimidazole resistance in the suspected strain cannot be confirmed.

引用

页码：85 / 92

页数：8

共 17 条

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