A POSSIBLE MOSAIC FORM OF DELAYED CENTROMERE SEPARATION AND ANEUPLOIDY

被引：10

作者：

MEHES, K

KOSZTOLANYI, G

机构：

[1] Department of Paediatrics, University Medical School of Pécs, Pécs, H-7623

来源：

HUMAN GENETICS | 1992年 / 88卷 / 04期

关键词：

D O I：

10.1007/BF00215686

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

On average, a "normal" centromere separation sequence was seen in 3 neonates with trisomy 18 and in their parents. When evaluating individual mitoses, unusually late separating chromosomes 18 were found in a few cells of one of the parents in each family. A possible germline mosaicism of delayed separation in the parent may account for trisomy in the offspring.

引用

页码：477 / 478

页数：2

共 10 条

[1] PARENTAL CENTROMERE SEPARATION SEQUENCE AND ANEUPLOIDY IN THE OFFSPRING [J].