THE SENSITIVE AND REACTIVE GUT

被引：10

作者：

MAYER, EA

机构：

[1] Departments of Medicine and Physiology, Gastroenteric Biology Center (CURE), VA Wadsworth Medical Center, University College of Los Angeles, Los Angeles, CA

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 1994年 / 6卷 / 06期

关键词：

CENTRAL SENSITIZATION; VISCERAL AFFERENTS; GASTROINTESTINAL MOTILITY;

D O I：

10.1097/00042737-199406000-00004

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Increased excitability of dorsal horn neurons receiving afferent input from the viscera provides a model which can explain both lowered visceral perception thresholds, and altered reflex responses which have been reported in patients with irritable bowel syndrome. Spinal hyperexcitability and associated visceral hyperalgesia can result from chemical, inflammatory or mechanical irritation of the gut, or via descending bulbospinal pathways.

引用

页码：470 / 477

页数：8

共 47 条

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