EFFECTIVENESS OF PNEUMATIC LEG COMPRESSION DEVICES FOR THE PREVENTION OF THROMBOEMBOLIC DISEASE IN ORTHOPEDIC TRAUMA PATIENTS - A PROSPECTIVE, RANDOMIZED STUDY OF COMPRESSION ALONE VERSUS NO PROPHYLAXIS

被引:109
作者
FISHER, CG [1 ]
BLACHUT, PA [1 ]
SALVIAN, AJ [1 ]
MEEK, RN [1 ]
OBRIEN, PJ [1 ]
机构
[1] UNIV BRITISH COLUMBIA,DEPT ORTHOPAED,VANCOUVER,BC,CANADA
关键词
PNEUMATIC LEG COMPRESSION DEVICES; THROMBOEMBOLIC DISEASE;
D O I
10.1097/00005131-199502000-00001
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
A prospective, randomized clinical trial in 304 orthopaedic trauma patients with hip and pelvic fractures was conducted to investigate the effectiveness of pneumatic sequential leg compression devices (PSLCDs) for the prevention of thromboembolic disease. The control group received no specific form of prophylaxis. Patients were followed by venous Doppler, duplex scan, and ventilation perfusion lung scans. The study end-point was documented pulmonary embolism and/or deep vein thrombosis. The incidence of a venous thromboembolic event in the control group was 11% and in the experimental group 4%. This difference was statistically significant (p = 0.02). These patients were also stratified into hip and pelvic fracture groups. In the hip fracture patients, the control group had a thromboembolic event incidence of 12% and the experimental group 4%. This difference was also statistically significant (p = 0.03). In the pelvic fracture group there was a thromboembolic incidence of 11% in the controls, demonstrating this patient population to be at significant risk. In this group, the PSLCDs were not statistically shown to be effective. Pneumatic leg compression devices are effective in reducing the incidence of thromboembolic events in patients with hip fractures.
引用
收藏
页码:1 / 7
页数:7
相关论文
共 37 条
[1]  
Ahlberg A., Nylander G., Robertson B., Dextran in prophylaxis of thrombosis in fractures of the hip, Acta Chir Scand, 387, pp. 83-85, (1968)
[2]  
Albrechtsson U., Olsson C.G., Thrombotic side-effects of lower limb phlebography, Lancet, 1, pp. 723-724, (1976)
[3]  
Baker S.P., O'Neill B., Haddon W., Long W.B., The injury severity score: A method for describing patients with multiple injuries and evaluating emergency care, J Trauma, 14, pp. 187-196, (1974)
[4]  
Barnes R.W., Nix M.L., Barnes C.L., Et al., Perioperative asymptomatic venous thrombosis: Role of duplex scanning versus venography, J Vase Surg, 9, pp. 251-260, (1989)
[5]  
Bergquist D., Efsing H.O., Hallbook T., Hedlund T., Thromboembolism after elective and post-traumatic hip surgery—a controlled, prophylactic trial with Dextran 70 and low-dose heparin, Acta Chir Stand, 145, pp. 213-218, (1979)
[6]  
Bergquist D., Efsing H.O., Hallbrook T., Lindblad B., Prevention of postoperative thromboembolic complications: A prospective comparison between Dextran 70, dihydro-ergotamine, heparin and sulphated polysaccharide, Acta Chir St And, 146, pp. 559-564, (1980)
[7]  
Coe N.P., Collins R.E., Klein L.A., Et al., Prevention of deep vein thrombosis in urological patients. A controlled, randomized trial of low-dose heparin and external pneumatic compression boots, Surgery, 83, pp. 230-234, (1978)
[8]  
Collins R., Scrimgeour A., Yusuf S., Peto R., Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin. Overview of results of randomized trials in general, orthopedic, and uro-logic surgery, N Engl J Med, 318, pp. 1162-1173, (1988)
[9]  
Cranley J.J., Higgins R.F., Ford C.R., Berry R.E., Comerota A.J., Griffin L.H., Duplex Scanning Correlated with Phlebography. A Multi-Center Study [Abstract], (1988)
[10]  
Evarts C.M., Feil E.J., Prevention of thromboembolic disease after elective surgery of the hip, J Bone Joint Surg [Am], 53, pp. 1271-1280, (1971)