TREATMENT OF GUILLAIN-BARRE-SYNDROME WITH ANTI-T-CELL MONOCLONAL-ANTIBODIES

被引：18

作者：

FEASBY, TE ^{[1
]}

机构：

[1] UNIV WESTERN ONTARIO,DEPT CLIN NEUROL SCI,LONDON N6A 3K7,ONTARIO,CANADA

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1991年 / 54卷 / 01期

关键词：

D O I：

10.1136/jnnp.54.1.51

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Three patients with acute Guillain-Barre syndrome were treated early in the course of the disease with OKT3, an anti-T-cell monoclonal antibody. Each patient developed acute lymphopenia with specific depletion of T3-positive lymphocytes. Two patients had continued progression of clinical deficits for eight and 14 days. This suggests that T lymphocytes may not be essential for progression of Guillain-Barre syndrome at this stage of the disease.

引用

页码：51 / 54

页数：4

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