A RELIABLE METHOD FOR DETERMINATION OF URINARY ESTRIOL IN PREGNANCY

被引：22

作者：

GOEBELSMANN, U

机构：

[1] Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, Mich

来源：

CLINICA CHIMICA ACTA | 1969年 / 23卷 / 03期

关键词：

D O I：

10.1016/0009-8981(69)90351-9

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

A reliable method for the estimation of urinary estriol in pregnancy is presented. This method is based upon acid hydrolysis, solvent partition, methylation and chromatography. Estriol is measured by colorimetry using the Kober reaction. All results are corrected for procedural loss by adding tritium-labelled estriol-16-glucosiduronate to the unhydrolyzed urine. This method proves to be sufficiently specific, accurate and precise. One operator may complete six assays within one working day. It is emphasized that a comprehensive recovery control which includes the initial hydrolytic procedure is essential if estriol determinations are to serve as a diagnostic aid in obstetrics. © 1968.

引用

页码：469 / +

页数：1

共 19 条

[1]

BELING CG, 1963, ACTA ENDOCRINOL S79

[2] CHEMICAL METHOD FOR THE DETERMINATION OF OESTRIOL, OESTRONE AND OESTRADIOL IN HUMAN URINE [J].