AZIDOTHYMIDINE INHIBITS MITOGEN STIMULATED GROWTH AND DNA-REPAIR IN HUMAN PERIPHERAL LYMPHOCYTES

被引：25

作者：

MUNCHPETERSEN, B

机构：

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1988年 / 157卷 / 03期

关键词：

D O I：

10.1016/S0006-291X(88)81026-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1369 / 1375

页数：7

共 18 条

[1]

BIRNBOIM HC, 1981, CANCER RES, V41, P1889

[2]

BOYUM A, 1968, SCAND J CLIN LAB INV, VS 21, P51

[3] THE EFFICACY OF AZIDOTHYMIDINE (AZT) IN THE TREATMENT OF PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].

FISCHL, MA ;

RICHMAN, DD ;

GRIECO, MH ;

GOTTLIEB, MS ;

VOLBERDING, PA ;

LASKIN, OL ;

LEEDOM, JM ;

GROOPMAN, JE ;

MILDVAN, D ;

SCHOOLEY, RT ;

JACKSON, GG ;

DURACK, DT ;

KING, D .

NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (04) :185-191

[4] PHOSPHORYLATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND SELECTIVE INTERACTION OF THE 5'-TRIPHOSPHATE WITH HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE [J].

FURMAN, PA ;

FYFE, JA ;

STCLAIR, MH ;

WEINHOLD, K ;

RIDEOUT, JL ;

FREEMAN, GA ;

LEHRMAN, SN ;

BOLOGNESI, DP ;

BRODER, S ;

MITSUYA, H ;

BARRY, DW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (21) :8333-8337

[5] PLASMA AND CEREBROSPINAL-FLUID PHARMACOKINETICS OF 3'-AZIDO-3'-DEOXYTHYMIDINE - A NOVEL PYRIMIDINE ANALOG WITH POTENTIAL APPLICATION FOR THE TREATMENT OF PATIENTS WITH AIDS AND RELATED DISEASES [J].

KLECKER, RW ;

COLLINS, JM ;

YARCHOAN, R ;

THOMAS, R ;

JENKINS, JF ;

BRODER, S ;

MYERS, CE .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1987, 41 (04) :407-412

[6] FRACTIONATION OF DNA FROM MAMMALIAN-CELLS BY ALKALINE ELUTION [J].

KOHN, KW ;

ERICKSON, LC ;

EWIG, RAG ;

FRIEDMAN, CA .

BIOCHEMISTRY, 1976, 15 (21) :4629-4637

[7] INHIBITION OF HIV-ASSOCIATED REVERSE-TRANSCRIPTASE BY SUGAR-MODIFIED DERIVATIVES OF THYMIDINE 5'-TRIPHOSPHATE IN COMPARISON TO CELLULAR DNA POLYMERASE-ALPHA AND POLYMERASE-BETA [J].

MATTHES, E ;

LEHMANN, C ;

SCHOLZ, D ;

VONJANTALIPINSKI, M ;

GAERTNER, K ;

ROSENTHAL, HA ;

LANGEN, P .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 148 (01) :78-85

[8] UV SENSITIVITY IN THYMIDINE KINASE DEFICIENT MOUSE ERYTHROLEUKEMIA-CELLS [J].

MCKENNA, PG ;

HICKEY, I .

CELL BIOLOGY INTERNATIONAL REPORTS, 1981, 5 (06) :555-561

[9] 3'-AZIDO-3'-DEOXYTHYMIDINE (BW A509U) - AN ANTIVIRAL AGENT THAT INHIBITS THE INFECTIVITY AND CYTOPATHIC EFFECT OF HUMAN LYMPHOTROPIC-T VIRUS TYPE-III LYMPHADENOPATHY-ASSOCIATED VIRUS INVITRO [J].

MITSUYA, H ;

WEINHOLD, KJ ;

FURMAN, PA ;

STCLAIR, MH ;

LEHRMAN, SN ;

GALLO, RC ;

BOLOGNESI, D ;

BARRY, DW ;

BRODER, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (20) :7096-7100

[10]

MUNCHPETERSEN B, 1985, MOL CELL BIOCHEM, V66, P185

← 1 2 →