RADIOIMMUNOASSAY OF CARDIAC MYOSIN LIGHT CHAIN-II IN THE SERUM FOLLOWING EXPERIMENTAL MYOCARDIAL-INFARCTION

被引：27

作者：

NAGAI, R

UEDA, S

YAZAKI, Y

机构：

[1] Cardiovascular Research Unit, The Third Department of Internal Medicine, Faculty of Medicine, Tokyo

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 86卷 / 03期

关键词：

D O I：

10.1016/0006-291X(79)91767-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A sensitive radioimmunoassay of cardiac myosin light chain II (LC II) was developed, and changes of serum LC II levels were studied in experimental myocardial infarction in dogs. In our assay, 0.2-5 ng of LC II were effectively measurable. The time-course curves of serum LC II level after coronary occlusion had two characteristics which had not been observed in serum enzyme studies; 1. (1) LC II level rose rapidly and stayed up during a long period, 2. (2) changes of serum LC II levels were biphasic in some cases . © 1979.

引用

页码：683 / 688

页数：6

共 5 条

[1] PREPARATION OF IODINE-131 LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC ACTIVITY
HUNTER, WM
GREENWOOD, FC
[J]. NATURE, 1962, 194 (4827) : 495 - &
[2] LOWRY OH, 1951, J BIOL CHEM, V193, P265
[3] FRACTIONATION OF LIGHT-CHAINS FROM RAT AND RABBIT CARDIAC MYOSIN
YAZAKI, Y
MOCHINAGA, S
RABEN, MS
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 328 (02) : 464 - 469
[4] EFFECT OF THYROID STATE ON ENZYMATIC CHARACTERISTICS OF CARDIAC MYOSIN - DIFFERENCE IN BEHAVIOR OF RAT AND RABBIT CARDIAC MYOSIN
YAZAKI, Y
RABEN, MS
[J]. CIRCULATION RESEARCH, 1975, 36 (01) : 208 - 215
[5] YAZAKI Y, 1978, RECENT ADV STUDIES C, V12, P39

← 1 →