ANTIBIOTIC-TREATMENT OF RICKETTSIOSIS, RECENT ADVANCES AND CURRENT CONCEPTS

被引:21
作者
RAOULT, D
机构
[1] Centre National de Référence Unité des Rickettsias C.H.U. La Timone, Marseille Cedex 05, 13385
关键词
RICKETTSIOSIS; Q-FEVER; ANTIBIOTICS; TREATMENT;
D O I
10.1007/BF00145677
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The author reviews the recent advances in the treatment of Mediterranean Spotted Fever and Q fever. In mediterranean spotted fever (M.S.F.), in vitro and preliminary in vivo data support the place of quinolones and josamycin in the treatment of M.S.F. In children josamycin could become the first choice drug as well as in pregnant woman. In Q fever chronic disease should be treated using a combination of antibiotic (doxycycline + quinolones) for a minimum of 3 years.
引用
收藏
页码:276 / 281
页数:6
相关论文
共 45 条
  • [1] Barker C.F., Determination of antibiotic susceptibility of Rickettsiae and Chlamydiae in BS-C-1 cell cultures, Antimicrob. Agents Chemother., 1969, 1968, pp. 425-428, (1986)
  • [2] Bella F., Font B., Uriz S., Munoz Espin T., Espejo Arenas E., Traveria J., Serrano J.A., Segura F., Randomized trial of Doxycycline versus Josamycin for Mediterranean Spotted Fever, Antimicrob. Agents Chemother., 34, pp. 937-938, (1990)
  • [3] Bella Cueto F., Font Creus B., Segura Porta F., Espejo Arenas E., Lopez Pares P., Munoz Espin T., Comparative, randomized trial of one day Doxycycline versus 10/day Tetracycline therapy for Mediterranean Spotted Fever, J. Infect. Dis., 155, pp. 1056-1058, (1987)
  • [4] Bertrand A., Jambon F., Jonquet O., Reynes J., Infections par les rickettsiales et fluoroquinolones, Path. Biol., 36, pp. 493-495, (1988)
  • [5] Drancourt M., Raoult D., In vitro susceptibilities of Rickettsia rickettsii and Rickettsia conorii to Roxithromycin and Pristinamycin., Antimicrob. Agents Chemother., 33, pp. 2146-2148, (1989)
  • [6] Fishbein D.B., Frontini M.G., Giles R., Vernon L.L., Fatal cases of Rocky Mountain Spotted Fever in the United States, 1981–1988, Ann. N.Y. Acad. Sc., 590, pp. 246-247, (1990)
  • [7] Freeman R., Hodson M., Q fever endocarditis treated with Trimethoprimsulfamethoxazole, Br. Med. J., 1, (1972)
  • [8] Guchiol F., Pallares R., Carratala J., Bolao F., Ariza J., Ruft G., Viladrich R.E., Randomized Double-blind evaluation of Ciprofloxacin and Doxycycline for Mediterranean Spotted Fever, Antimicrob. Agents Chemother., 33, pp. 987-988, (1989)
  • [9] Hackstadt T., Willia J.C., Biochemical stratagem for obligate parasitism of eukaryotic cells by Coxiella burnetii, Proc. Natl. Acad. Sci. USA, 78, pp. 3240-3244, (1981)
  • [10] Huebner R.J., Hottle G.A., Robinson E.B., Action of Streptomycin in experimental infection with Q fever, Publ. Health Rept., 63, (1948)