MODULATION OF THE IMMUNE-RESPONSE AND CONTROL OF TUMOR SPREAD BY A NEW SYNTHETIC COMPOUND

被引：18

作者：

FALK, RE

MAKOWKA, L

NOSSAL, N

FALK, JA

FIELDS, JE

ASCULAI, SS

机构：

[1] MONSANTO CO, ST LOUIS, MO 63166 USA

[2] TORONTO GEN HOSP, ROTMAN ONCOL UNIT, TORONTO, ONTARIO, CANADA

来源：

BRITISH JOURNAL OF SURGERY | 1979年 / 66卷 / 12期

关键词：

D O I：

10.1002/bjs.1800661208

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

A small molecular weight biofunctional polymer, NED 137, has been investigated for its anti‐neoplastic effect. Through its effect on the immune system, particularly the induction of B cell differentiation to antibody producing cells, this synthetic compound can retard tumour growth and prevent the development of distant metastases. Reactivity to tumour developed following administration of the NED 137. No toxicity has been observed. The polymer NED 137 is now being tested in phase I and phase II clinical trials. Copyright © 1979 British Journal of Surgery Society Ltd.

引用

页码：861 / 863

页数：3

共 8 条

[1] DETECTION OF HOMOGRAFT SENSITIVITY IN MICE BY ELIMINATION OF CHROMIUM-51 LABELED LYMPH NODE CELLS [J].