The CREB family of transcription activators

被引:273
作者
Brindle, Paul K. [1 ,2 ]
Montminy, Marc R. [1 ,2 ]
机构
[1] Salk Inst Biol Sci, La Jolla, CA 92037 USA
[2] Salk Inst, Clayton Fdn Labs Peptide Biol, San Diego, CA 92186 USA
关键词
D O I
10.1016/S0959-437X(05)80274-6
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
A diverse family of transcription factors bind to the CAMP-response elements found in a variety of mammalian and viral gene promoters. One of the members of this family, CREB, is being intensively studied so as to elucidate the mechanisms by which second messenger signal transduction pathways act to positively and negatively regulate transcription.
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页码:199 / 204
页数:6
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