EVIDENCE FOR TACHYKININ NK-2B-LIKE RECEPTORS IN GUINEA-PIG ALVEOLAR MACROPHAGES

被引：15

作者：

BRUNELLESCHI, S

CENI, E

FANTOZZI, R

MAGGI, CA

机构：

[1] A MENARINI PHARMACEUT, I-50131 FLORENCE, ITALY

[2] UNIV TURIN, INST PHARMACOL, I-10125 TURIN, ITALY

来源：

LIFE SCIENCES | 1992年 / 51卷 / 20期

关键词：

D O I：

10.1016/0024-3205(92)90626-Z

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Mammalian tachykinins dose-dependently activate guinea-pig alveolar macrophages, by interacting with tachykinin NK-2 receptors, mainly. By evaluating the effects of different NK-2 tachykinin receptor antagonists, we now provide evidence that tachykinin NK-2 receptors in guinea-pig alveolar macrophages meet the pharmacological criteria used to define the NK-2B subtype.

引用

收藏

页码：PL177 / PL181

页数：5

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