PURE PROGRESSIVE AUTONOMIC FAILURE - A CLINICOPATHOLOGICAL STUDY

被引：14

作者：

TERAO, Y

TAKEDA, K

SAKUTA, M

NEMOTO, T

TAKEMURA, T

KAWAI, M

机构：

[1] JAPANESE RED CROSS MED CTR, DEPT NEUROL, TOKYO, TOKYO, JAPAN

[2] JAPANESE RED CROSS MED CTR, DEPT PATHOL, TOKYO, TOKYO, JAPAN

来源：

EUROPEAN NEUROLOGY | 1993年 / 33卷 / 06期

关键词：

PURE PROGRESSIVE AUTONOMIC FAILURE; PARKINSONS DISEASE; DORSAL ROOT GANGLIA; AUTONOMIC FUNCTION TEST;

D O I：

10.1159/000116985

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Two cases of pure progressive autonomic failure (PAF) are presented. A postmortem study of one case (case 2) showed a pathology resembling that of Parkinson's disease. Marked cell loss was noted in the substantia nigra, nucleus ceruleus, and intermediolateral column of the spinal cord, while cell loss in the sympathetic ganglion was not remarkable. This case may be an exceptionally rare case of late-onset PAF in which autonomic failure was mainly ascribed to preganglionic (and central) pathology, although autonomic function tests suggested postganglionic sympathetic disorder in both cases.

引用

页码：409 / 415

页数：7

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