ABOLITION OF THE EXPRESSION OF INHIBITORY GUANINE-NUCLEOTIDE REGULATORY PROTEIN-GI ACTIVITY IN DIABETES

被引：253

作者：

GAWLER, D

MILLIGAN, G

SPIEGEL, AM

UNSON, CG

HOUSLAY, MD

机构：

[1] ROCKEFELLER UNIV,DEPT BIOCHEM,NEW YORK,NY 10021

[2] NIDDKD,METAB DIS BRANCH,BETHESDA,MD 20892

来源：

NATURE | 1987年 / 327卷 / 6119期

关键词：

D O I：

10.1038/327229a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：229 / 232

页数：4

共 23 条

[1] DETECTION OF THE MAJOR PERTUSSIS TOXIN SUBSTRATE OF HUMAN-LEUKOCYTES WITH ANTISERA RAISED AGAINST SYNTHETIC PEPTIDES
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[2] ISLET-ACTIVATING PROTEIN BLOCKS GLUCAGON DESENSITIZATION IN INTACT HEPATOCYTES
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[3] INSULIN INHIBITS THE CHOLERA-TOXIN-CATALYZED RIBOSYLATION OF A MR-25000 PROTEIN IN RAT-LIVER PLASMA-MEMBRANES
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[J]. BIOCHEMICAL JOURNAL, 1985, 228 (03) : 593 - 603
[4] THE ACTION OF ISLET ACTIVATING PROTEIN (PERTUSSIS TOXIN) ON INSULIN ABILITY TO INHIBIT ADENYLATE-CYCLASE AND ACTIVATE CYCLIC-AMP PHOSPHODIESTERASES IN HEPATOCYTES
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[J]. BIOCHEMICAL JOURNAL, 1986, 235 (01) : 145 - 149
[5] INSULIN AND GLUCAGON REGULATE THE ACTIVATION OF 2 DISTINCT MEMBRANE-BOUND CYCLIC-AMP PHOSPHODIESTERASES IN HEPATOCYTES
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[J]. BIOCHEMICAL JOURNAL, 1983, 214 (01) : 99 - 110
[6] HILDEBRANDT JD, 1982, J BIOL CHEM, V257, P4723
[7] A FAMILY OF GUANINE-NUCLEOTIDE REGULATORY PROTEINS
HOUSLAY, MD
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1984, 9 (02) : 39 - 40
[8] CHOLERA TOXIN MEDIATED ACTIVATION OF ADENYLATE-CYCLASE IN INTACT RAT HEPATOCYTES
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ELLIOTT, KRF
[J]. FEBS LETTERS, 1979, 104 (02) : 359 - 363
[9] HOUSLAY MD, 1985, MOL ASPECTS CELL REG, V4, P279
[10] ITOH H, 1984, J BIOL CHEM, V259, P5464

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