CHANGES IN END-PLATE VASCULARITY AFTER AN OUTER ANULUS TEAR IN THE SHEEP

被引：112

作者：

MOORE, RJ

OSTI, OL

VERNONROBERTS, B

FRASER, RD

机构：

[1] Division of Tissue Pathology, Institute o f Medical and Veterinary Science, SA

[2] Department of Pathology, University of Adelaide

[3] Department of Orthopaedic Surgery, Trauma Royal Adelaide Hospital, Adelaide, SA

来源：

SPINE | 1992年 / 17卷 / 08期

关键词：

INTERVERTEBRAL DISK; CARTILAGE END PLATE; NUTRITION; VASCULAR CHANNELS; DISK DEGENERATION;

D O I：

10.1097/00007632-199208000-00003

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In 31 2-year-old sheep, a 5-mm deep cut was made parallel to the end plates in the left anterolateral anulus fibrosus of 3 randomly selected lumbar intervertebral discs. At 2 months, the area of the end plate occupied by blood vessels on the left (operated) side had increased significantly (P < 0.05) in the cranial end plate to 9.94%, and to 9.39% in the caudal end plate, compared with nonoperated values of 5.17% (cranial) and 5.87% (caudal). One year after operation, these elevated values had diminished significantly (P < 0.05) to 7.92% (cranial) and 7.13% (caudal), and continued to decline progressively to 7.48% (cranial) and 6.88% (caudal) by 2 years. In contrast, no significant differences were found on the right (nonoperated) side of the discs. Thus, there was an early proliferation of vascular channels in the end plate in the vicinity of the experimental anular lesion, but not on the nonoperated side of the same disc. Thereafter, the end plate vascularity progressively diminished toward a normal level.

引用

页码：874 / 878

页数：5

共 14 条

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