HYPOGLYCEMIC ACTIVITY OF OLIVE LEAF

被引：129

作者：

GONZALEZ, M

ZARZUELO, A

GAMEZ, MJ

UTRILLA, MP

JIMENEZ, J

OSUNA, I

机构：

[1] UNIV GRANADA, FAC FARM, DEPT FARMACOL, E-18071 GRANADA, SPAIN

[2] UNIV GRANADA, FAC MED, DEPT BIOQUIM, E-18071 GRANADA, SPAIN

来源：

PLANTA MEDICA | 1992年 / 58卷 / 06期

关键词：

OLEA-EUROPAEA; OLIVE LEAF; HYPOGLYCEMIC ACTIVITY; OLEUROPEOSIDE; SEASONAL VARIATION;

D O I：

10.1055/s-2006-961538

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The hypoglycemic activity of olive leaf was studied. Maximum hypoglycemic activity was obtained from samples collected in the winter months, especially in February. One of the compounds responsible for this activity was oleuropeoside, which showed activity at a dose of 16 mg/kg. This compound also demonstrated antidiabetic activity in animals with alloxan-induced diabetes. The hypoglycemic activity of this compound may result from two mechanisms: (a) potentiation of glucose-induced insulin release, and (b) increased peripheral uptake of glucose.

引用

页码：513 / 515

页数：3

共 10 条

[1]

CAPRETTI G, 1948, GIORN CLIN MED, V29, P491

[2]

LECLERC H, 1954, REV PHYTOTHER, V18, P7

[3]

MURILLO A, 1972, REV ESP FISIOL, V28, P115

[4]

OSUNA JI, 1985, PHOSPHATASE MINERAL, P509

[5]

Panizzi L., 1960, GAZZ CHIM ITAL, V90, P1449

[6]

RANDAVEL C, 1948, CR SOC BIOL, V142, P394

[7]

SOLZ A, 1974, REV ESP FISIOL, V3, P207

[8]

VALLANCEOWEN J, 1954, LANCET, V1, P68

[9] VASODILATOR EFFECT OF OLIVE LEAF [J].

ZARZUELO, A ;

DUARTE, J ;

JIMENEZ, J ;

GONZALEZ, M ;

UTRILLA, MP .

PLANTA MEDICA, 1991, 57 (05) :417-419

[10]

1954, FARMACOPEA ESPANOLA, V9, P396

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