SURVEY OF THE ALLERGIC STATUS OF PATIENTS WITH BRONCHIAL-ASTHMA IN TURKEY - A MULTICENTER STUDY

被引:40
作者
KALYONCU, AF
COPLU, L
SELCUK, ZT
EMRI, AS
KOLACAN, B
KOCABAS, A
ERKAN, L
SAHIN, AA
AKKOCLU, A
BARIS, YI
机构
[1] HACETTEPE UNIV,FAC MED,DEPT CHEST DIS,ANKARA 06100,TURKEY
[2] GEN SOCIAL INSURANCE AGCY HOSP,DEPT CHEST DIS,ELAZIG,TURKEY
[3] CUKUROVA UNIV,FAC MED,DEPT CHEST DIS,ADANA,TURKEY
[4] DOKUZ EYLUL UNIV,FAC MED,DEPT CHEST DIS,IZMIR,TURKEY
[5] ONDOKUZ MAYIS UNIV,FAC MED,DEPT CHEST DIS,SAMSUN,TURKEY
关键词
ALLERGEN SPECTRUM; ATOPY; BRONCHIAL ASTHMA; GEOGRAPHIC DIFFERENCES IN ALLERGY; TOTAL IGE; TURKEY;
D O I
10.1111/j.1398-9995.1995.tb01177.x
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Patients diagnosed with bronchial asthma (BA) were prospectively enrolled to assess their allergen spectra and atopic status. The patients came from five major cities (Ankara, Izmir, Samsun, EIazig, and Adana) in different regions of Turkey. Atopic status, total IgE levels, and allergen spectra were determined in 1149 patients and 210 controls who were spouses of the patients sharing the same environment but not consanguinity with the patients. Total IgE levels were significantly higher in the asthmatic patients. For both groups, total IgE levels were higher in both atopic and male subjects. Atopy rates were 42% in asthmatics and 26.1% in controls, declining notably by age in both groups. The most commnon allergen in both groups was house-dust mite (HDM), which was more frequently detected in coastal regions (Samsun, Izmir, and Adana). Allergen spectra of the patients included HDM, pollens, cockroach, pet animals, and molds in decreasing order of frequency. Phleum pratense and Artemisia vulgaris were the most common pollens in all regions, whereas Olea europaea was the most common in Izmir. Pollen sensitivity was least frequent in Elazig. For all of the regions, pet sensitivity was less common than, and mold sensitivity was comparable to, that of Western countries. In conclusion, BA patients in Turkey displayed significant differences in their allergen spectra and total IgE levels from control subjects and BA patients in Western countries.
引用
收藏
页码:451 / 455
页数:5
相关论文
共 15 条
  • [1] DISTRIBUTION OF IGE IN A COMMUNITY POPULATION-SAMPLE - CORRELATIONS WITH AGE, SEX, AND ALLERGEN SKIN-TEST REACTIVITY
    BARBEE, RA
    HALONEN, M
    LEBOWITZ, M
    BURROWS, B
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1981, 68 (02) : 106 - 111
  • [2] RESPIRATORY DISORDERS AND ALLERGY SKIN-TEST REACTIONS
    BURROWS, B
    LEBOWITZ, MD
    BARBEE, RA
    [J]. ANNALS OF INTERNAL MEDICINE, 1976, 84 (02) : 134 - 139
  • [3] BURROWS B, 1989, NEW ENGL J MED, V268, P271
  • [4] DISTRIBUTION OF ALLERGY IN A POPULATION-SAMPLE RESIDING IN TUCSON, ARIZONA
    CLINE, MG
    BURROWS, B
    [J]. THORAX, 1989, 44 (05) : 425 - 431
  • [5] SERUM TOTAL IGE LEVELS IN A REPRESENTATIVE SAMPLE OF A GREEK POPULATION .1. CORRELATION WITH AGE, SEX, AND SKIN REACTIVITY TO COMMON AEROALLERGENS
    GRIGOREAS, C
    PAPPAS, D
    GALATAS, ID
    KOLLIAS, G
    PAPADIMOS, S
    PAPADAKIS, P
    [J]. ALLERGY, 1993, 48 (03) : 142 - 146
  • [6] GURPINAR T, 1978, HERBAL FLORAL CHARAC, P32
  • [7] ANALYSIS OF SKIN PRICK TEST REACTIONS IN 656 ASTHMATIC-PATIENTS
    HENDRICK, DJ
    DAVIES, RJ
    DSOUZA, MF
    PEPYS, J
    [J]. THORAX, 1975, 30 (01) : 2 - 8
  • [8] IDENTIFICATION OF COMMON ALLERGENIC STRUCTURES IN HAZEL POLLEN AND HAZELNUTS - A POSSIBLE EXPLANATION FOR SENSITIVITY TO HAZELNUTS IN PATIENTS ALLERGIC TO TREE POLLEN
    HIRSCHWEHR, R
    VALENTA, R
    EBNER, C
    FERREIRA, F
    SPERR, WR
    VALENT, P
    ROHAC, M
    RUMPOLD, H
    SCHEINER, O
    KRAFT, D
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1992, 90 (06) : 927 - 936
  • [9] SERUM IGE LEVELS AND ALLERGIC SPECTRA IN IMMIGRANTS TO SWEDEN
    KALYONCU, AF
    STALENHEIM, G
    [J]. ALLERGY, 1992, 47 (04) : 277 - 280
  • [10] MOSS RB, 1989, ANN ALLERGY, V63, P566