INDUCTION OF GERM-CELL FORMATION BY OSKAR

被引：530

作者：

EPHRUSSI, A ^{[1
]}

LEHMANN, R ^{[1
]}

机构：

[1] MIT,HOWARD HUGHES MED INST,WHITEHEAD INST BIOMED RES,DEPT BIOL,CAMBRIDGE,MA 02142

来源：

NATURE | 1992年 / 358卷 / 6385期

关键词：

D O I：

10.1038/358387a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The oskar gene directs germ plasm assembly and controls the number of germ cell precursors formed at the posterior pole of the Drosophila embryo. Mislocalization of oskar RNA to the anterior pole leads to induction of germ cells at the anterior. Of the eight genes necessary for germ cell formation at the posterior, only three, oskar, vasa and tudor, are essential at an ectopic site.

引用

页码：387 / 392

页数：6

共 41 条

[1] THE ROLE OF LOCALIZATION OF BICOID RNA IN ORGANIZING THE ANTERIOR PATTERN OF THE DROSOPHILA EMBRYO
BERLETH, T
BURRI, M
THOMA, G
BOPP, D
RICHSTEIN, S
FRIGERIO, G
NOLL, M
NUSSLEINVOLHARD, C
[J]. EMBO JOURNAL, 1988, 7 (06) : 1749 - 1756
[2] TUDOR, A GENE REQUIRED FOR ASSEMBLY OF THE GERM PLASM IN DROSOPHILA-MELANOGASTER
BOSWELL, RE
MAHOWALD, AP
[J]. CELL, 1985, 43 (01) : 97 - 104
[3] BOSWELL RE, 1991, DEVELOPMENT, V113, P373
[4] BICAUDAL A GENETIC FACTOR WHICH AFFECTS POLARITY OF EMBRYO IN DROSOPHILA MELANOGASTER
BULL, AL
[J]. JOURNAL OF EXPERIMENTAL ZOOLOGY, 1966, 161 (02): : 221 - +
[5] A GRADIENT OF BICOID PROTEIN IN DROSOPHILA EMBRYOS
DRIEVER, W
NUSSLEINVOLHARD, C
[J]. CELL, 1988, 54 (01) : 83 - 93
[6] EDDY EM, 1975, INT REV CYTOL, V43, P229
[7] ELDON ED, 1991, DEVELOPMENT, V111, P367
[8] OSKAR ORGANIZES THE GERM PLASM AND DIRECTS LOCALIZATION OF THE POSTERIOR DETERMINANT NANOS
EPHRUSSI, A
DICKINSON, LK
LEHMANN, R
[J]. CELL, 1991, 66 (01) : 37 - 50
[9] ORGANIZATION OF ANTERIOR PATTERN IN THE DROSOPHILA EMBRYO BY THE MATERNAL GENE BICOID
FROHNHOFER, HG
NUSSLEINVOLHARD, C
[J]. NATURE, 1986, 324 (6093) : 120 - 125
[10] ANALYSIS OF KRUPPEL PROTEIN DISTRIBUTION DURING EARLY DROSOPHILA DEVELOPMENT REVEALS POSTTRANSCRIPTIONAL REGULATION
GAUL, U
SEIFERT, E
SCHUH, R
JACKLE, H
[J]. CELL, 1987, 50 (04) : 639 - 647

← 1 2 3 4 5 →