CHOLECYSTOKININ ANTAGONISTS - SYNTHESIS AND BIOLOGICAL EVALUATION OF 3-SUBSTITUTED 1,4-BENZODIAZEPIN-2-AMINES

被引：22

作者：

BOCK, MG ^{[1
]}

DIPARDO, RM ^{[1
]}

EVANS, BE ^{[1
]}

RITTLE, KE ^{[1
]}

FREIDINGER, RM ^{[1
]}

CHANG, RSL ^{[1
]}

LOTTI, VJ ^{[1
]}

机构：

[1] MERCK SHARP & DOHME RES LABS,DEPT MICROBIAL PHARMACOMETR,W POINT,PA 19486

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 01期

关键词：

D O I：

10.1021/jm00396a042

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：264 / 268

页数：5

共 35 条

[1] QUINAZOLINES + 1,4-BENZODIAZEPINES .16. SYNTHESIS + TRANSFORMATIONS OF 5-PHENYL-1,4-BENZODIAZEPINE-2-THIONES
ARCHER, GA
STERNBACH, LH
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1964, 29 (01) : 231 - &
[2] CHOLECYSTOKININ IN THE CENTRAL NERVOUS-SYSTEM - A MINIREVIEW
BEINFELD, MC
[J]. NEUROPEPTIDES, 1983, 3 (06) : 411 - 427
[3] BERNTHSEN A, 1876, J LIEBIGS ANN CHEM, V184, P321
[4] AN EXPEDIENT SYNTHESIS OF 3-AMINO-1,3-DIHYDRO-5-PHENYL-2H-1,4-BENZODIAZEPIN-2-ONE
BOCK, MG
DIPARDO, RM
EVANS, BE
RITTLE, KE
VEBER, DF
FREIDINGER, RM
[J]. TETRAHEDRON LETTERS, 1987, 28 (09) : 939 - 942
[5] SYNTHESIS AND RESOLUTION OF 3-AMINO-1,3-DIHYDRO-5-PHENYL-2H-1,4-BENZODIAZEPIN-2-ONES
BOCK, MG
DIPARDO, RM
EVANS, BE
RITTLE, KE
VEBER, DF
FREIDINGER, RM
HIRSHFIELD, J
SPRINGER, JP
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (15) : 3232 - 3239
[6] TOTAL SYNTHESIS OF NONPEPTIDAL CHOLECYSTOKININ ANTAGONISTS FROM ASPERGILLUS-ALLIACEUS
BOCK, MG
DIPARDO, RM
PITZENBERGER, SM
HOMNICK, CF
SPRINGER, JP
FREIDINGER, RM
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1987, 52 (08) : 1644 - 1646
[7] BOCK MG, IN PRESS J MED CHEM
[8] BENZODIAZEPINES ANTAGONIZE CHOLECYSTOKININ-INDUCED ACTIVATION OF RAT HIPPOCAMPAL-NEURONS
BRADWEJN, J
DEMONTIGNY, C
[J]. NATURE, 1984, 312 (5992) : 363 - 364
[9] ANTAGONISM OF CHOLECYSTOKININ-INDUCED ACTIVATION BY BENZODIAZEPINE RECEPTOR AGONISTS - MICROIONTOPHORETIC STUDIES IN THE RAT HIPPOCAMPUS
BRADWEJN, J
DEMONTIGNY, C
[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1985, 448 (JUL) : 575 - 580
[10] INCREASE IN BRAIN I-125-LABELED CHOLECYSTOKININ (CCK) RECEPTOR-BINDING FOLLOWING CHRONIC HALOPERIDOL TREATMENT, INTRACISTERNAL 6-HYDROXYDOPAMINE OR VENTRAL TEGMENTAL LESIONS
CHANG, RSL
LOTTI, VJ
MARTIN, GE
CHEN, TB
[J]. LIFE SCIENCES, 1983, 32 (08) : 871 - 878

← 1 2 3 4 →