A CONCISE SYNTHESIS OF PENEMS

被引：2

作者：

BARKER, AJ

CAMPBELL, MM

JENKINS, MJ

机构：

[1] HOECHST PHARMACEUT RES LABS,MILTON KEYNES MK7 7AJ,ENGLAND

[2] UNIV BATH,SCH CHEM,BATH BA2 7AY,AVON,ENGLAND

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(00)97622-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A brief and efficient new synthesis of 2-substituted 6-11 (R)-hydroxyethyl]-penems is described. The key step involves reaction of an azetidin-2-one-4-disulphide with either stabilized or unstabilized phosphoranes, giving ylids which cyclize with the 1-oxalimide group to give 2 -substituted penems. © 1990.

引用

页码：4359 / 4362

页数：4

共 19 条

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