SPERM MORPHOLOGICAL ASSESSMENT BASED ON STRICT CRITERIA AND INVITRO FERTILIZATION OUTCOME

被引：57

作者：

KOBAYASHI, T

JINNO, M

SUGIMURA, K

NOZAWA, S

SUGIYAMA, T

IIDA, E

机构：

[1] Department of Obstetrics and Gynaecology, School of Medicine, Keio University, Shinjuku-ku, Tokyo 160

[2] Department of Obstetrics and Gynaecology, Ogikubo Hospital, Tokyo

来源：

HUMAN REPRODUCTION | 1991年 / 6卷 / 07期

关键词：

SPERM MORPHOLOGY; FERTILIZATION INVITRO; HUMAN; PREGNANCY; MISCARRIAGE;

D O I：

10.1093/oxfordjournals.humrep.a137473

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

One-hundred-and-twenty-three in-vitro fertilization (IVF) cycles were analysed in order to clarify the influence of strictly normal morphology (SNM) of spermatozoa on IVF outcome. SNM was defined using strict criteria according to Kruger with our modifications. The IVF cycles studied were divided into three groups: %SNM < 12% (13 cycles), 12 < 40% (68 cycles), greater-than-or-equal-to 40% (42 cycles). The cleavage rates per oocyte were higher in the groups with 12-40% and greater-than-or-equal-to 40% of %SNM than in the group with %SNM < 12%. The embryo transfer rate per cycle increased with increasing %SNM. The overall pregnancy rate per cycle increased with increasing %SNM (7.7% in %SNM < 12%,22.1% in 12-40% of %SNM, and 40.5% in %SNM greater-than-or-equal-to 40%). The ongoing pregnancy rate per cycle also increased with increasing %SNM (7.7% in %SNM < 12%,14.7% in 12-40% of %SNM, and 31.0% in %SNM greater-than-or-equal-to 40%). The miscarriage rate was lower in %SNM greater-than-or-equal-to 40% (23.5%) than in 12-40% of %SNM (33.3%). It was suggested that %SNM is a good predictor of IVF outcome.

引用

页码：983 / 986

页数：4

共 17 条

[1]

Alper M.M., Lee G.S., Seibel M.M., Smith D., Oskowitz S.P., Ransil B.J., Taymor M.L., The relationship of semen parameters to fertilization in patients participating in a program of in vitro fertilization, J in Vitro Fertil Embryo Transfer, 2, pp. 217-223, (1985)

[2]

Chan S.Y.W., Wang C., Chan S.T.H., Ho P.C., So W.W.K., Chan Y.F., Ma H.K., Predictive value of sperm morphology and movement characteristics in the outcome of in vitro fertilization of human oocytes, J in Vitro Fertil Embryo Transfer, 6, pp. 142-148, (1989)

[3]

Hirsch I., Gibbons W.E., Lipshultz L.I., Rossavik K.K., Young R.L., Poindexter A.N., Dodson M.G., Findley W.E., In vitro fertilization in couples with male factor infertility, Fertil. Steril, 15, pp. 659-664, (1986)

[4]

Jeulin C., Feneux D., Serres C., Jouannet P., Guillet-Rosso F., Belaisch-Allart J., Frydman R., Testart J., Sperm factors related to failure of human in-vitro fertilization, J. Reprod. Fertil, 76, pp. 735-744, (1986)

[5]

Jinno M., Comparison of media used for human in vitro fertilization and embryo transfer programs: A new method of serum preparation, Acta Obstet. Gynaecol. Jpn, 38, pp. 102-110, (1986)

[6]

Jinno M., Kobayashi T., Sugimura K., Iizuka R., Iida E., Kuji N., Strictly normal sperm morphology is a very important parameter to predict the outcome of human IVF-ET, The Xllth Asian & Oceanic Congress on Obstetrics & Gynecology, Taipei, Taiwan. R. O. C., Abstr. No. FC4-B, (1989)

[7]

Kruger T.F., Menkveld R., Stander F.S.H., Lombard C.J., Van Der Merwe J.P., Van Zyl J.A., Smith K., Sperm morphologic features as a prognostic factor in in vitro fertilization, Fertil. Steril, 46, pp. 1118-1123, (1986)

[8]

Kruger T.F., Acosta A.A., Simmons K.F., Swanson R.J., Matta J.F., Veeck L.L., Morshedi M., Brugo S., New method of evaluating sperm morphology with predictive value for human in vitro fertilization, Urology, 30, pp. 248-251, (1987)

[9]

Kruger T.F., Ackerman S.B., Simmons K.F., Swanson R.J., Brugo S.S., Acosta A.A., A quick, reliable staining technique for human sperm morphology, Arch. Androl, 18, pp. 275-277, (1987)

[10]

Kruger T.F., Acosta A.A., Simmons K.F., Swanson R.J., Matta J.F., Oehninger S., Predictive value of abnormal sperm morphology in in vitro fertilization, Fertil. Steril, 49, pp. 112-117, (1988)

← 1 2 →