APPLICATION OF GAMMA-CYCLODEXTRIN TO ENANTIOMERIC PURITY DETERMINATION OF A NEW 2-AMINO-TETRALIN DERIVATIVE BY H-1-NMR SPECTROSCOPY

被引：9

作者：

REDENTI, E ^{[1
]}

FRONZA, G ^{[1
]}

BOVIS, G ^{[1
]}

VENTURA, P ^{[1
]}

机构：

[1] CNR,CTR STUDIO SOSTANZE ORGAN NAT,DIPARTIMENTO CHIM,I-20133 MILAN,ITALY

来源：

CHIRALITY | 1992年 / 4卷 / 06期

关键词：

NMR SHIFT REAGENT; 2-AMINO TETRALIN; CYCLODEXTRIN; ENANTIOMERIC EXCESS; OPTICAL PURITY;

D O I：

10.1002/chir.530040613

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Gamma-Cyclodextrin was used to perform chiral discrimination of (+/-)-5,6-diisobutyroyl-2-methylaminotetralin hydrochloride by H-1-NMR; the 95% enantiomeric excess of the (-)-isomer was determined successfully.

引用

页码：404 / 405

页数：2