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THE ROLE OF BRAHMA AND RELATED PROTEINS IN TRANSCRIPTION AND DEVELOPMENT

被引：59
作者：
TAMKUN, JW
机构：
[1] 323 Sinsheimer Laboratories, Department of Biology, University of California, Santa Cruz
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1995年 / 5卷 / 04期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/0959-437X(95)90051-H
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The differential transcription of Drosophila homeotic genes is maintained by the Polycomb and trithorax groups of regulatory proteins, many of which are thought to modulate chromatin structure. During the past year, studies of a trithorax group member, brahma, and related yeast and human proteins have suggested that they are components of huge complexes that assist DNA-binding regulatory proteins to overcome the repressive effects of chromatin on transcription.
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页码：473 / 477
页数：5
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