PYRUVATE CARBOXYLASE OF RHIZOPUS NIGRICANS AND ITS ROLE IN FUMARIC ACID PRODUCTION

被引：28

作者：

OVERMAN, SA

ROMANO, AH

机构：

[1] Department of Biological Sciences, Graduate Division of Microbiology, University of Cincinnati, Cincinnati

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 37卷 / 03期

关键词：

D O I：

10.1016/0006-291X(69)90937-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The chief carbon dioxide-fixing system in a fumaric acid-producing strain of Rhizopus nigricans is an acetyl coenzyme A - dependent pyruvate carboxylase. This enzyme is produced in high levels during the period of rapid glucose utilization, and precedes fumarate accumulation. It is proposed that this system is the principal anaplerotic CO2 fixing mechanism in this organism, and its continued operation in high glucose media after biosynthesis has ceased results in production of fumaric acid. © 1969.

引用

页码：457 / &

共 12 条

[1]

BLOOM SJ, 1962, J BIOL CHEM, V237, P2718

[2] A SIMPLE EFFICIENT LIQUID SCINTILLATOR FOR COUNTING AQUEOUS SOLUTIONS IN A LIQUID SCINTILLATION COUNTER [J].