TUMOR-NECROSIS-FACTOR ALPHA GENE POLYMORPHISM IN MULTIPLE-SCLEROSIS AND OPTIC NEURITIS

被引：40

作者：

FUGGER, L ^{[1
]}

MORLING, N ^{[1
]}

SANDBERGWOLLHEIM, M ^{[1
]}

RYDER, LP ^{[1
]}

SVEJGAARD, A ^{[1
]}

机构：

[1] UNIV LUND HOSP,DEPT NEUROL,S-22185 LUND,SWEDEN

来源：

JOURNAL OF NEUROIMMUNOLOGY | 1990年 / 27卷 / 01期

关键词：

Gene polymorphism; Multiple sclerosis; Optic neuritis; Tumor necrosis factor;

D O I：

10.1016/0165-5728(90)90140-I

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The NcoI tumor necrosis factor (TNFα) polymorphism was studied in relapwing/remitting multiple sclerosis and monosymptomatic optic neuritis. The frequency of the NcoI marker phenotypes did not differ between healthy controls and the two disease groups. No extra or missing DNA fragments were observed in the disease groups when compared with controls. © 1990.

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页码：85 / 88

页数：4

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