STRUCTURAL HOMOLOGY AMONG THE PEROXIDASE ENZYME FAMILY REVEALED BY HYDROPHOBIC CLUSTER-ANALYSIS

被引：54

作者：

HENRISSAT, B ^{[1
]}

SALOHEIMO, M ^{[1
]}

LAVAITTE, S ^{[1
]}

KNOWLES, JKC ^{[1
]}

机构：

[1] VALT TEKNILLINEN TUTKIMUSKESKUS, BIOTECH LAB, SF-02150 ESPOO, FINLAND

来源：

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS | 1990年 / 8卷 / 03期

关键词：

active site; hydrophobic cluster analysis; peroxidase; sequence comparison; structure conservation;

D O I：

10.1002/prot.340080307

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A number of peroxidase amino acid sequences show limited homology to short regions comprising the known active site cleft of yeast cytochrome c peroxidase. Otherwise no clear homology is visible in linear alignments between this enzyme and other peroxidases. We have subjected eight peroxidase sequences to hydrophobic cluster analysis. Our results suggest that these peroxidases are evolutionary related and that they share many folding characteristics. Copyright © 1990 Wiley‐Liss, Inc.

引用

页码：251 / 257

页数：7

共 23 条

[1]

ARGOS P, 1988, GENETIC ENG PRINCIPL, V10, P21

[2]

BAIROCH A, 1989, SWISS PROT PROTEIN S

[3] DETERMINANTS OF A PROTEIN FOLD - UNIQUE FEATURES OF THE GLOBIN AMINO-ACID-SEQUENCES [J].

BASHFORD, D ;

CHOTHIA, C ;

LESK, AM .

JOURNAL OF MOLECULAR BIOLOGY, 1987, 196 (01) :199-216

[4] MULTIPLE SEQUENCE ALIGNMENT WITH HIERARCHICAL-CLUSTERING [J].

CORPET, F .

NUCLEIC ACIDS RESEARCH, 1988, 16 (22) :10881-10890

[5] PROBING STRUCTURE-FUNCTION RELATIONS IN HEME-CONTAINING OXYGENASES AND PEROXIDASES [J].

DAWSON, JH .

SCIENCE, 1988, 240 (4851) :433-439

[6]

DAYHOFF MO, 1978, ATLAS PROTEIN SEQUEN, V5, P1

[7] ANALYSIS OF NUCLEOTIDE-SEQUENCES OF 2 LIGNINASE CDNAS FROM A WHITE-ROT FILAMENTOUS FUNGUS, PHANEROCHAETE-CHRYSOSPORIUM [J].

DEBOER, HA ;

ZHANG, YZ ;

COLLINS, C ;

REDDY, CA .

GENE, 1987, 60 (01) :93-102

[8] CLONING AND SEQUENCING OF CHLOROPEROXIDASE CDNA [J].

FANG, GH ;

KENIGSBERG, P ;

AXLEY, MJ ;

NUELL, M ;

HAGER, LP .

NUCLEIC ACIDS RESEARCH, 1986, 14 (20) :8061-8071

[9]

FINZEL BC, 1984, J BIOL CHEM, V259, P3027

[10] HYDROPHOBIC CLUSTER-ANALYSIS - AN EFFICIENT NEW WAY TO COMPARE AND ANALYZE AMINO-ACID-SEQUENCES [J].

GABORIAUD, C ;

BISSERY, V ;

BENCHETRIT, T ;

MORNON, JP .

FEBS LETTERS, 1987, 224 (01) :149-155

← 1 2 3 →