REACTIVITY AND SYNTHETIC APPLICATIONS OF BIS(IMINOPHOSPHORANES) - ONE-POT PREPARATION OF PYRIDO[2,3,4-DE]QUINAZOLINES AND BENZO[DE][1,6]NAPHTHYRIDINES

被引：42

作者：

MOLINA, P

ALJARIN, M

VIDAL, A

机构：

[1] Departamento de Química Orgánica, Facultad de Química, Universidad de Murcia, Campus de Espinardo, E-30071, Murcia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 25期

关键词：

D O I：

10.1021/jo00051a007

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aza-Wittig reaction of bis(iminophosphorane) 4 with 2 equiv of isocyanate leads directly to pyrido[2,3,4-de]quinazolines 5. Iminophosphoranes 8, available from 4 and 1 equiv of the appropriate isocyanate, react either with 1 equiv of isocyanate or ketene to give pyrido[2,3,4-de]quinazolines 9 or benzo[de][1,6]naphthyridines 10, respectively. Bis(iminophosphorane) 4 by sequential treatment with aldehydes and isocyanates yielded 2,3-dihydropyrido[2,3,4-de]quinazolines 17.

引用

页码：6703 / 6711

页数：9

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