INCREASING RESISTANCE TO PENICILLIN IN STREPTOCOCCUS-PNEUMONIAE IN SOUTHERN SWEDEN

被引：34

作者：

EKDAHL, K

KAMME, C

机构：

[1] UNIV LUND HOSP,DEPT CLIN MICROBIOL,S-22362 LUND,SWEDEN

[2] UNIV LUND HOSP,DEPT INFECT DIS,S-22362 LUND,SWEDEN

来源：

SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES | 1994年 / 26卷 / 03期

关键词：

D O I：

10.3109/00365549409011799

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The susceptibility to penicillin of 6 prevalent pneumococcal types isolated from nasopharynx in 1992 was compared with that of corresponding types from 1980-82. The 6 types or groups, 6, 9, 14, 15, 19 and 23, constituted 78% of consecutive isolates. 19/204 isolates in 1992 were intermediately resistant (MIC 0.12-1.0 mg/l) in comparison with 1/194 from 1980-82 (p < 0.001). Resistant strains (MIC greater than or equal to 2 mg/l) were not found. Of group 15, no fewer than 10/31 isolates were intermediately resistant, which may support the clonal origin and spread of penicillin-resistant pneumococci. At least 5.0% of nasopharyngeal isolates are now intermediately resistant to penicillin. This figure is substantially higher than the 2% earlier reported in Sweden.

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页码：301 / 305

页数：5

相关论文

共 22 条

[1]

APPLEBAUM PC, 1992, CLIN INFECT DIS, V15, P77

[2] A REVIEW OF ANTIBIOTIC-RESISTANCE PATTERNS OF STREPTOCOCCUS-PNEUMONIAE IN EUROPE [J].

BAQUERO, F ;

MARTINEZBELTRAN, J ;

LOZA, E .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1991, 28 :31-38

[3] INTRA-SPECIFIC AND INTER-SPECIFIC TRANSFORMATION OF STREPTOCOCCUS-PNEUMONIAE TO PENICILLIN RESISTANCE [J].

CHALKLEY, LJ ;

KOORNHOF, HJ .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1990, 26 (01) :21-28

[4]

COL NF, 1987, REV INFECT DIS S3, V9, P232

[5] HORIZONTAL TRANSFER OF PENICILLIN-BINDING PROTEIN GENES IN PENICILLIN-RESISTANT CLINICAL ISOLATES OF STREPTOCOCCUS-PNEUMONIAE [J].

DOWSON, CG ;

HUTCHISON, A ;

BRANNIGAN, JA ;

GEORGE, RC ;

HANSMAN, D ;

LINARES, J ;

TOMASZ, A ;

SMITH, JM ;

SPRATT, BG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (22) :8842-8846

[6] PENICILLIN-RESISTANT VIRIDANS STREPTOCOCCI HAVE OBTAINED ALTERED PENICILLIN-BINDING PROTEIN GENES FROM PENICILLIN-RESISTANT STRAINS OF STREPTOCOCCUS-PNEUMONIAE [J].

DOWSON, CG ;

HUTCHISON, A ;

WOODFORD, N ;

JOHNSON, AP ;

GEORGE, RC ;

SPRATT, BG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (15) :5858-5862

[7] ISOLATION OF NASOPHARYNGEAL BETA-LACTAMASE PRODUCING HEMOPHILUS-INFLUENZAE, IN RELATION TO ANTIBIOTIC-TREATMENT OF ACUTE OTITIS-MEDIA IN INFANTS [J].

FREIJD, A ;

RYNNELDAGOO, B .

ACTA OTO-LARYNGOLOGICA, 1983, 95 (3-4) :351-357

[8] ANTIMICROBIAL RESISTANCE IN STREPTOCOCCUS-PNEUMONIAE - AN EPIDEMIOLOGIC SURVEY IN FRANCE, 1970-1990 [J].

GESLIN, P ;

BUUHOI, A ;

FREMAUX, A ;

ACAR, JF .

CLINICAL INFECTIOUS DISEASES, 1992, 15 (01) :95-98

[9] ALTERATIONS IN PENICILLIN-BINDING PROTEINS OF CLINICAL AND LABORATORY ISOLATES OF PATHOGENIC STREPTOCOCCUS-PNEUMONIAE WITH LOW-LEVELS OF PENICILLIN RESISTANCE [J].

HANDWERGER, S ;

TOMASZ, A .

JOURNAL OF INFECTIOUS DISEASES, 1986, 153 (01) :83-89

[10]

JONSSON L, 1992, SELEKTION AV BETA LA