HETEROGENEITY OF DUCT CARCINOMA IN-SITU (DCIS) - RELATIONSHIP OF GRADE AND SUBTYPE ANALYSIS TO LOCAL RECURRENCE AND RISK OF INVASIVE TRANSFORMATION

被引：57

作者：

LAGIOS, MD ^{[1
]}

机构：

[1] ST MARYS HOSP,CANC CONSULTAT SERV,SAN FRANCISCO,CA

来源：

CANCER LETTERS | 1995年 / 90卷 / 01期

关键词：

BREAST CONSERVATION THERAPY; DISEASE FREE SURVIVAL; DUCT CARCINOMA IN SITU; NUCLEAR GRADE; PATHOLOGICAL CLASSIFICATION; PROGNOSIS;

D O I：

10.1016/0304-3835(94)03683-A

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Morphologic analysis of nuclear grade and extent of necrosis can provide reproducible classification of subclinical duct carcinoma in situ (DCIS) which strongly separates DCIS into three risk groups. For subclinical lesions of small size, risk is largely limited to local recurrences only, half of which, however, are invasive events. Local recurrences are seen much more frequently with high grade DCIS. Most local recurrences following breast conservation therapy represent residual disease in the immediate vicinity of the biopsy site. Stromal and cellular host reactions may provide additional prognostic information.

引用

页码：97 / 102

页数：6

共 36 条

[1] FOLLOW-UP OF 2 TREATMENT MODALITIES FOR DUCTAL CANCER INSITU OF THE BREAST [J].