EFFECTS OF CEREBRAL INTRA-VENTRICULAR MAGNESIUM INJECTIONS AND A LOW MAGNESIUM DIET ON NONSPECIFIC EXCITABILITY LEVEL, AUDIOGENIC-SEIZURE SUSCEPTIBILITY AND SEROTONIN

被引：14

作者：

BUCK, DR

MAHONEY, AW

HENDRICKS, DG

机构：

[1] UTAH STATE UNIV,COLL FAMILY LIFE,DEPT NUTR & FOOD SCI 87,LOGAN,UT 84322

[2] UTAH STATE UNIV,COLL AGR,LOGAN,UT 84322

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1979年 / 10卷 / 04期

关键词：

Behavior; Brain; Intraventricular; Magnesium deficiency; Magnesium pharmacology; Serotonin;

D O I：

10.1016/0091-3057(79)90222-3

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Cerebral intraventricular injections of 17 and 50 μg magnesium in artificial cerebrospinal fluid progressivelt depressed the Non-specific Excitability Level of permanently cannulated 150-200 g rats fed a low magnesium diet for 21 days. Compared with control diet, a low Mg diet caused an increase in brain serotonin. Weanling rats fed a low Mg diet for 2 weeks, then injected with 25 μg Mg via acute cannulations, displayed reduced audiogenic seizure susceptibility compared with sham-injected controls. © 1979.

引用

页码：487 / 491

页数：5

共 21 条

[1] INDUCTION AND REVERSAL OF MAGNESIUM-DEFICIENCY SYNDROME IN INBRED MICE [J].