POTENTIAL ANTI-TUMOR AGENTS .10. CYTOTOXIC NORDITERPENE DILACTONES OF PODOCARPUS-MILANJIANUS AND PODOCARPUS-SELLOWII

被引:29
作者
HEMBREE, JA
CHANG, CJ
MCLAUGHLIN, JL
CASSADY, JM
WATTS, DJ
WENKERT, E
FONSECA, SF
CAMPELLO, JDP
机构
[1] PURDUE UNIV,SCH PHARM & PHARMACAL SCI,DEPT MED CHEM & PHARMACOGNOSY,W LAFAYETTE,IN 47907
[2] INDIANA UNIV,DEPT CHEM,BLOOMINGTON,IN 47401
[3] UNIV ESTADUAL CAMPINAS,INST QUIM,CAMPINAS 13100,SP,BRAZIL
关键词
9KB cytotoxicity; bark; nagilactone F; nagilactone G; norditerpene dilactones; Podocarpaceae; Podocarpus milanjianus and Podocarpus sellowii; structural analysis;
D O I
10.1016/0031-9422(79)80185-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The cytotoxic norditerpene dilactones nagilactone F and its new congener nagilactone G have been isolated from the bark constituents of Podocarpus milanjianus and Podocarpus sellowii. The diterpenes totarol, 19-oxototarol and macrophyllic acid were also isolated. © 1979.
引用
收藏
页码:1691 / 1694
页数:4
相关论文
共 24 条