CHANGES IN SERUM ALUMINUM, BLOOD ZINC, BLOOD LEAD AND ERYTHROCYTE DELTA-AMINOLEVULINIC-ACID DEHYDRATASE ACTIVITY DURING HEMODIALYSIS

被引：43

作者：

MEREDITH, PA ^{[1
]}

ELLIOTT, HL ^{[1
]}

CAMPBELL, BC ^{[1
]}

MOORE, MR ^{[1
]}

机构：

[1] UNIV GLASGOW,WESTERN INFIRM,GARDINER INST,DEPT MED,GLASGOW G11 6NT,SCOTLAND

来源：

TOXICOLOGY LETTERS | 1979年 / 4卷 / 05期

关键词：

D O I：

10.1016/0378-4274(79)90055-9

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

In a study of 18 patients on haemodialysis, erythrocyte δ-aminolaevulinic acid dehydratase (ALAD), serum aluminium, blood zinc and blood lead concentrations were increased significantly following haemodialysis. The increase in erythrocyte ALAD activity was found to be significantly linearly correlated with the increase in blood zinc concentrations. In comparison with control subjects, the patients had significantly lower activities of ALAD and significantly increased serum aluminium concentrations. When zinc and lead concentrations were corrected for packed cell volume they were found to be significantly higher in the patient group than in the control group. © 1979.

引用

页码：419 / 424

页数：6

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