REPRODUCTION NUMBERS AND THRESHOLDS IN STOCHASTIC EPIDEMIC MODELS .1. HOMOGENEOUS POPULATIONS

被引:52
作者
JACQUEZ, JA
ONEILL, P
机构
[1] UNIV MICHIGAN,DEPT BIOSTAT,ANN ARBOR,MI 48109
[2] UNIV NOTTINGHAM,DEPT MATH,NOTTINGHAM NG7 2RD,ENGLAND
关键词
D O I
10.1016/0025-5564(91)90003-2
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We compare threshold results for the deterministic and stochastic versions of the homogeneous SI model with recruitment, death due to the disease, a background death rate, and transmission rate beta-cXY/N. If an infective is introduced into a population of susceptibles, the basic reproduction number, R0, plays a fundamental role for both, though the threshold results differ somewhat. For the deterministic model, no epidemic can occur if R0 less-than-or-equal-to 1 and an epidemic occurs if R0 > 1. For the stochastic model we find that on average, no epidemic will occur if R0 less-than-or-equal-to 1. If R0 > 1, there is a finite probability, but less than 1, that an epidemic will develop and eventuate in an endemic quasi-equilibrium. However, there is also a finite probability of extinction of the infection, and the probability of extinction decreases as R0 increases above 1.
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页码:161 / 186
页数:26
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