THE FORMATION AND PERSISTENCE OF BENZO(A)PYRENE METABOLITE-DEOXYRIBONUCLEOSIDE ADDUCTS IN RAT SKIN INVIVO

被引：26

作者：

ASHURST, SW

COHEN, GM

机构：

[1] UNIV LONDON,SCH PHARM,DEPT PHARMACOL,TOXICOL UNIT,LONDON WC1N 1AX,ENGLAND

[2] UNIV SURREY,DEPT BIOCHEM,GUILDFORD GU2 5XH,SURREY,ENGLAND

来源：

INTERNATIONAL JOURNAL OF CANCER | 1981年 / 28卷 / 03期

关键词：

D O I：

10.1002/ijc.2910280319

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：387 / 392

页数：6

共 36 条

[1] BENZO[A]PYRENE-7,8-DIHYDRODIOL-9,10-EPOXIDE IS THE MAJOR METABOLITE INVOLVED IN THE BINDING OF BENZO[A]PYRENE TO DNA IN ISOLATED VIABLE RAT HEPATOCYTES [J].

ASHURST, SW ;

COHEN, GM .

CHEMICO-BIOLOGICAL INTERACTIONS, 1980, 29 (01) :117-127

[2] INVIVO FORMATION OF BENZO(A)PYRENE DIOL EPOXIDE-DEOXYADENOSINE ADDUCTS IN THE SKIN OF MICE SUSCEPTIBLE TO BENZO(A)PYRENE-INDUCED CARCINOGENESIS [J].

ASHURST, SW ;

COHEN, GM .

INTERNATIONAL JOURNAL OF CANCER, 1981, 27 (03) :357-364

[3] MAGNESIUM-IONS AFFECT THE QUANTITATIVE BUT NOT THE QUALITATIVE MICROSOME MEDIATED BINDING OF BENZO[A]-PYRENE TO DNA [J].

ASHURST, SW ;

COHEN, GM .

CHEMICO-BIOLOGICAL INTERACTIONS, 1979, 28 (2-3) :279-289

[4] METABOLISM OF BENZO[A]PYRENE BY CULTURED TRACHEO-BRONCHIAL TISSUES FROM MICE, RATS, HAMSTERS, BOVINES AND HUMANS [J].

AUTRUP, H ;

WEFALD, FC ;

JEFFREY, AM ;

TATE, H ;

SCHWARTZ, RD ;

TRUMP, BF ;

HARRIS, CC .

INTERNATIONAL JOURNAL OF CANCER, 1980, 25 (02) :293-300

[5]

BAIRD W M, 1973, Cancer Research, V33, P2378

[6]

BAIRD WM, 1980, POLYNUCLEAR AROMATIC, P471

[7]

BERENBLUM I, 1949, JNCI-J NATL CANCER I, V10, P167

[8] EVIDENCE FOR BINDING OF POLYNUCLEAR AROMATIC HYDRO-CARBONS TO NUCLEIC ACIDS OF MOUSE SKIN - RELATION BETWEEN CARCINOGENIC POWER OF HYDROCARBONS + THEIR BINDING TO DEOXYRIBONUCLEIC ACID [J].

BROOKES, P ;

LAWLEY, PD .

NATURE, 1964, 202 (493) :781-&

[9]

COHEN GM, 1979, CANCER RES, V39, P4027

[10]

COHEN GM, 1980, POLYNUCLEAR AROMATIC, P503

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