LUTEOMA OF PREGNANCY - STEROIDOGENIC AND MORPHOLOGIC CONSIDERATIONS

被引：20

作者：

RICE, BF

BARCLAY, DL

STERNBERG, WH

机构：

[1] Division of Endocrine Research, Section II, Alton Ochsner Medical Foundation New Orleans, LA

[2] Department of Pathology, Tulane University School of Medicine New Orleans, LA

[3] Department of Obstetrics, Tulane University School of Medicine New Orleans, LA

[4] Department of Gynecology, Tulane University School of Medicine New Orleans, LA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1969年 / 104卷 / 06期

关键词：

D O I：

10.1016/0002-9378(69)90639-5

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Steroid hormone content and steroid synthesis in vitro were studied in a clinically and morphologically typical luteoma of pregnancy. The only Δ4-3-ketosteroid present was tentatively identified by paper and thin-layer chromatography as Δ4-androstene-3,17-dione. Net synthesis (μg) of this androgen was augmented in vitro by HCG. No radioactive steroid formation from acetate-1-14C could be established after analysis by reverse isotope dilution. The biochemical and histologic data suggest that the luteoma of pregnancy originates from the ovarian stroma. The augmentation of steroidogenesis by HCG in vitro in this study and the clinical observation of postpartum regression in other studies are compatible with the concept that the placental gonadotropin plays some role in development and maintenance of this specific ovarian lesion. © 1969.

引用

页码：871 / +

页数：1

共 18 条

[1]

DIVINO LE, 1966, OBSTET GYNECOL, V28, P842

[2] LUTEOMAS OF PREGNANCY [J].