PP60C-SRC TYROSINE KINASE, MYRISTYLATION, AND MODULATORY DOMAINS ARE REQUIRED FOR ENHANCED MITOGENIC RESPONSIVENESS TO EPIDERMAL GROWTH-FACTOR SEEN IN CELLS OVEREXPRESSING C-SRC

被引：113

作者：

WILSON, LK

LUTTRELL, DK

PARSONS, JT

PARSONS, SJ

机构：

[1] UNIV VIRGINIA,SCH MED,DEPT MICROBIOL,CHARLOTTESVILLE,VA 22908

[2] UNIV VIRGINIA,SCH MED,CTR CANC,CHARLOTTESVILLE,VA 22908

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1989年 / 9卷 / 04期

关键词：

D O I：

10.1128/MCB.9.4.1536

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1536 / 1544

页数：9

共 51 条

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[3] BRUGGE JS, 1984, J BIOL CHEM, V259, P4550
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[5] MYRISTIC ACID, A RARE FATTY-ACID, IS THE LIPID ATTACHED TO THE TRANSFORMING PROTEIN OF ROUS-SARCOMA VIRUS AND ITS CELLULAR HOMOLOG
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[6] THE ABSENCE OF MYRISTIC ACID DECREASES MEMBRANE-BINDING OF P60SRC BUT DOES NOT AFFECT TYROSINE PROTEIN-KINASE ACTIVITY
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[J]. JOURNAL OF VIROLOGY, 1986, 58 (02) : 468 - 474
[7] CELL-TRANSFORMATION BY PP60C-SRC MUTATED IN THE CARBOXY-TERMINAL REGULATORY DOMAIN
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[J]. CELL, 1987, 49 (01) : 83 - 91
[8] ALTERED SITES OF TYROSINE PHOSPHORYLATION IN PP60C-SRC ASSOCIATED WITH POLYOMAVIRUS MIDDLE TUMOR-ANTIGEN
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ECKHART, W
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1986, 6 (05) : 1562 - 1570
[9] ALTERED PHOSPHORYLATION AND ACTIVATION OF PP60C-SRC DURING FIBROBLAST MITOSIS
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SHALLOWAY, D
[J]. CELL, 1988, 52 (06) : 801 - 810
[10] MUTATIONS AROUND THE NG59 LESION INDICATE AN ACTIVE ASSOCIATION OF POLYOMA-VIRUS MIDDLE-T ANTIGEN WITH PP60C-SRC IS REQUIRED FOR CELL-TRANSFORMATION
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[J]. EMBO JOURNAL, 1986, 5 (02) : 325 - 334

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