STUDIES ON THE DEVELOPMENT OF CELL CONTACTS AND OF THE INTER-CELLULAR MATRIX DURING DECIDUALIZATION IN THE RAT

Cell contacts between developing decidual cells were examined in thin sections and in replicas of freeze-cleaved tissue of rat uterus. At the time of implantation only puncta adhaerentia were found between stromal cells. Gap junctions appeared 24 h after decidualization and thereafter increased in number and extent. Thus, there is little morphological evidence for a propagation of the initial stimulus for decidualization via gap junctions. An increase in amorphous, extracellular material is noted after decidualization with a concomitant decrease of collagen fibers. This amorphous material probably represents fibrinoid. © 1979 J. F. Bergmann Verlag.